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Gene Expression Data
Assay Details
Assay
Reference: J:294897 Ankamreddy H, et al., CXCL12 is required for stirrup-shaped stapes formation during mammalian middle ear development. Dev Dyn. 2020 Sep;249(9):1117-1126
Assay type: RNA in situ
MGI Accession ID: MGI:7435273
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: Col2a1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: incus cartilage condensation Present 3B
TS22: malleus cartilage condensation Present 3B
TS22: stapes cartilage condensation Present 3B Control displays the stapedial foramen hole in the stapes.
Specimen 3E: embryonic day 14.5; Cxcl12tm1Spo/Cxcl12tm1Spo (more )
Structure Level Pattern Image Note
TS22: incus cartilage condensation Present 3E
TS22: malleus cartilage condensation Present 3E
TS22: stapes cartilage condensation Present 3E The stapedial foramen hole was not seen in the mutant staining.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory