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Gene Expression Data
Assay Details
Assay
Reference: J:332792 Horakova L, et al., Eda controls the size of the enamel knot during incisor development. Front Physiol. 2022;13:1033130
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7432641
Gene symbol: Eda
Gene name: ectodysplasin-A
Antibody: anti-EDA [C-17] (sc-18927)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Present Regionally restricted 1A Expression in dental lamina as well as in vestibular lamina in anterior area of mandible.
Specimen 1B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw epithelium Present Regionally restricted 1B Expression in anterior superficial area of oral epithelium interconnecting tooth germ with vestibular lamina, at base of incisor germ.
Specimen 1B': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: incisor Absent 1B' No expression in functional incisor germ.
TS22: enamel knot Absent 1B' No expression in enamel knot.
TS22: lower jaw epithelium Present Regionally restricted 1B' Expression in adjacent vestibular lamina externally to dental epithelium.
Specimen 1C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lower jaw epithelium Present Regionally restricted 1C Expression in anterior superficial area of oral epithelium interconnecting tooth germ with vestibular lamina, at base of incisor germ.
Specimen 1C': embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: incisor Absent 1C'
TS23: enamel knot Absent 1C'
TS23: lower jaw epithelium Present Regionally restricted 1C' Expression in adjacent vestibular lamina externally to dental epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory