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Gene Expression Data
Assay Details
Assay
Reference: J:198469 Yang Y, et al., Cyclin dependent kinase 5 is required for the normal development of oligodendrocytes and myelin formation. Dev Biol. 2013 Jun 15;378(2):94-106
Assay type: RNA in situ
MGI Accession ID: MGI:7432372
Gene symbol: Pdgfra
Gene name: platelet derived growth factor receptor, alpha polypeptide
Probe: Pdgfra cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Horseradish peroxidase
Results
Specimen 2M: postnatal day 14 (more )
Note: Double labeled: blue - Pdgfra; brown - BrdU.
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte precursor cell Present 2M
Specimen 2N: postnatal day 14; Cdk5tm1Bibb/Cdk5tm1Bibb, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant. Double labeled: blue - Pdgfra; brown - BrdU.
Structure Cell Type Level Pattern Image Note
TS28: corpus callosum oligodendrocyte precursor cell Present 2N Similar as in the wild-type. No significant differences in proliferation either. Quantified in Fig 2Q.
Specimen 2O: postnatal day 14 (more )
Note: Double labeled: blue - Pdgfra; brown - BrdU.
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex oligodendrocyte precursor cell Present 2O
Specimen 2P: postnatal day 14; Cdk5tm1Bibb/Cdk5tm1Bibb, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant. Double labeled: blue - Pdgfra; brown - BrdU.
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex oligodendrocyte precursor cell Present 2P Similar as in the wild-type. No significant differences in proliferation either. Quantified in Fig 2Q.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory