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Gene Expression Data
Assay Details
Assay
Reference: J:198469 Yang Y, et al., Cyclin dependent kinase 5 is required for the normal development of oligodendrocytes and myelin formation. Dev Biol. 2013 Jun 15;378(2):94-106
Assay type: RNA in situ
MGI Accession ID: MGI:7432367
Gene symbol: Plp1
Gene name: proteolipid protein (myelin) 1
Probe: Plp/DM20 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Horseradish peroxidase
Results
Specimen 2D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2D
TS28: corpus callosum Present 2D
Specimen 2E: postnatal day 7; Cdk5tm1Bibb/Cdk5tm1Bibb, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2E Reduced expression compared with the wild-type.
TS28: corpus callosum Present 2E Reduced expression compared with the wild-type.
Specimen 2H: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2H
TS28: corpus callosum Present 2H
Specimen 2I: postnatal day 14; Cdk5tm1Bibb/Cdk5tm1Bibb, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2I More severely reduced expression compared with the wild-type.
TS28: corpus callosum Present 2I More severely reduced expression compared with the wild-type.
Specimen 2J: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present 2J
Specimen 2K: postnatal day 7; Cdk5tm1Bibb/Cdk5tm1Bibb, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present 2K Reduced expression compared with the wild-type. Quantified in Fig 2L.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory