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Gene Expression Data
Assay Details
Assay
Reference: J:332642 Cohen-Gulkar M, et al., The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431198
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tubulin Beta III [clone TU-20) (MAB1637)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S1A: embryonic day 16.5; Lhx2tm1Monu/Lhx2tm1Monu (more )
Note: Double labeled: green - Tubb3; red - Vsx2 (assay MGI:7431199).
Structure Level Pattern Image Note
TS24: pigmented retinal epithelium Absent S1A'' , S1A'' inset , S1A , S1A inset

Specimen S1C: embryonic day 16.5; Lhx2tm1Monu/Lhx2tm1Monu, Tg(Dct-cre)1Apdn/0 (more )
Note: Conditional mutant. Double labeled: green - Tubb3; red - Vsx2 (assay MGI:7431199).
Structure Level Pattern Image Note
TS24: pigmented retinal epithelium Absent S1C'' inset , S1C inset , S1C , S1C'' Mis-expression not detected.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory