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Gene Expression Data
Assay Details
Assay
Reference: J:284573 Gao XL, et al., High-mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesis. J Biol Chem. 2020 Jan 10;295(2):468-480
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7429207
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase3
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S2J WT E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Weak Single cells S2J E18 WT
Specimen S2J mKO E18: embryonic day 18.0; Hmgn2tm1a(KOMP)Wtsi/Hmgn2tm1a(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Weak Single cells S2J E18 mKO Increased apoptosis was not noted in the mutant.
Specimen S2J WT P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Weak Single cells S2J P4 WT
Specimen S2J mKO P4: postnatal day 4; Hmgn2tm1a(KOMP)Wtsi/Hmgn2tm1a(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Weak Single cells S2J P4 mKO Increased apoptosis was not noted in the mutant.
Specimen S2J WT P14: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Weak Single cells S2J P14 WT
Specimen S2J mKO P14: postnatal day 14; Hmgn2tm1a(KOMP)Wtsi/Hmgn2tm1a(KOMP)Wtsi (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Weak Single cells S2J P14 mKO Increased apoptosis was not noted in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory