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Gene Expression Data
Assay Details
Assay
Reference: J:200708 Jin JZ, et al., Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation. Dev Biol. 2013 Sep 1;381(1):170-8
Assay type: RNA in situ
MGI Accession ID: MGI:7429039
Gene symbol: Mixl1
Gene name: Mix paired-like homeobox
Probe: Mixl1 probe3
Probe preparation: Antisense RNA
Results
Specimen 4G: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: mesendoderm Strong 4G
TS11: primitive streak Strong 4G
Specimen 4H: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: mesendoderm Strong 4H
TS11: primitive streak Strong 4H
Specimen 4I: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Criptotm1Mms/Criptotm2.2Mms (more )
Note: Conditional mutant. Severely affected mutant embryos that had no primitive streak and mesendoderm cells.
Structure Level Pattern Image Note
TS11: extraembryonic component Present Regionally restricted 4I Expressed in the proximal region.
Specimen 4J: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Criptotm1Mms/Criptotm2.2Mms (more )
Note: Conditional mutant. Less severely affected embryos that formed mesendoderm layer.
Structure Level Pattern Image Note
TS11: extraembryonic component Present 4J
TS11: mesendoderm Present Regionally restricted 4J Only expressed in mesendoderm cells near the edge of the embryonic region.
TS11: primitive streak Trace 4J
Specimen 4K: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Criptotm1Mms/Criptotm2.2Mms (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: primitive streak Trace 4K
TS11: mesendoderm Present Regionally restricted 4K No expression in the mesendoderm adjacent to the primitivestreak.
Specimen 4L: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Criptotm1Mms/Criptotm2.2Mms (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: mesendoderm Present Regionally restricted 4L Only expressed in mesendoderm cells near the edge of the embryonic region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory