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Gene Expression Data
Assay Details
Assay
Reference: J:200708 Jin JZ, et al., Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation. Dev Biol. 2013 Sep 1;381(1):170-8
Assay type: RNA in situ
MGI Accession ID: MGI:7429023
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Probe: Brachyury probe35
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 1A
Specimen 1B: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 1B
TS11: embryo mesoderm Present Regionally restricted 1B The mesoderm cells migrated out of the posterior region and were spread over the entire embryo.
Specimen 1D: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Criptotm1Mms/Criptotm2.2Mms (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: primitive streak Present 1D Expressed in an abnormal primitive streak area, which was shortened and widened.
Specimen 1E: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Criptotm1Mms/Criptotm2.2Mms (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo mesoderm Present Regionally restricted 1E Mesoderm cells accumulated in the posterior region within the abnormal primitive streak area, indicating a defect in lateral migration of mesoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory