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Gene Expression Data
Assay Details
Assay
Reference: J:207523 Edlund RK, et al., Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers. Dev Biol. 2014 Jun 1;390(1):1-13
Assay type: RNA in situ
MGI Accession ID: MGI:7428493
Gene symbol: Pitx1
Gene name: paired-like homeodomain transcription factor 1
Probe: Pitx1 probe15
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 8 WT 15ss: embryonic day 9.0 (more )
Note: 15 somites
Structure Level Pattern Image Note
TS14: 1st branchial arch Present 8_WT Pitx1 upper
Specimen 8 -/- 15ss: embryonic day 9.0; Foxi3tm1.2Akg/Foxi3tm1.2Akg (more )
Note: 15 somites
Structure Level Pattern Image Note
TS14: 1st branchial arch Present 8_-/- Pitx1upper Although the major morphological differences between the mutants and wild type embryos resulted in a noticeable decrease in expression area, the relative location in which it was expressed was unchanged.
Specimen 8 WT 25ss: embryonic day 9.5 (more )
Note: 25 somites
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 8_WT Pitx1 lower
Specimen 8 -/- 25ss: embryonic day 9.5; Foxi3tm1.2Akg/Foxi3tm1.2Akg (more )
Note: 25 somites
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 8_-/- Pitx1lower Although the major morphological differences between the mutants and wild type embryos resulted in a noticeable decrease in expression area, the relative location in which it was expressed was unchanged.
TS15: head mesenchyme Present Regionally restricted 8_-/- Pitx1lower Reduced expression in the in positive cells anterior to the 1st arch.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory