Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:319706 Silachev D, et al., Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutation. Acta Neuropathol Commun. 2022 Jan 28;10(1):9
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7425424
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved Caspase-3 (Asp175) (#9661)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

S5A +/+ ©

Specimen S5A +/+: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: cortical plate	Present		S5A +/+

S5A C215Y/+ ©

Specimen S5A C215Y/+: embryonic day 18.5; Gnao1^em2Katv/Gnao1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS26: cortical plate	Present		S5A C215Y/+	Immunostaining did not reveal any differences in apoptosis levels compared with wild type.

Specimen S5A C215Y/C215Y: embryonic day 18.5; Gnao1^em2Katv/Gnao1^em2Katv (more

)

Structure	Level	Pattern	Image	Note
TS26: cortical plate	Present		S5A C215Y/C215Y	Immunostaining did not reveal any differences in apoptosis levels compared with wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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