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Gene Expression Data
Assay Details
Assay
Reference: J:330830 Echevarria-Andino ML, et al., CDON contributes to Hedgehog-dependent patterning and growth of the developing limb. Dev Biol. 2022 Oct 17;493:1-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7411236
Gene symbol: Pdgfra
Gene name: platelet derived growth factor receptor, alpha polypeptide
Antibody: anti-Pdgfra (#3174)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2D: embryonic day 10.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Triple labeled: green - Pdgfra; blue - Cdh1 (assay MGI:7411237); red - Cre reporter.
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present 2D
Specimen 2G: embryonic day 10.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant. Triple labeled: green - Pdgfra; blue - Cdh1 (assay MGI:7411237); red - Cre reporter.
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present 2G Cre activity was restricted to Pdgfra+ lateral plate mesoderm.
Specimen 2J: embryonic day 10.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Triple labeled: green - Pdgfra; blue - Cdh1 (assay MGI:7411237); red - Cre reporter.
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present 2J
Specimen 2M: embryonic day 10.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant. Triple labeled: green - Pdgfra; blue - Cdh1 (assay MGI:7411237); red - Cre reporter.
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present 2M Cre activity was restricted to Pdgfra+ lateral plate mesoderm. Incomplete recombination was seen.
Specimen S1E/G: embryonic day 10.5; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant. Triple labeled: green - Pdgfra; blue - Cdh1 (assay MGI:7411237); red - Cre reporter.
Structure Level Pattern Image Note
TS17: hindlimb bud mesenchyme Present S1G , S1E Cre activity was restricted to Pdgfra+ lateral plate mesoderm. Incomplete recombination was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory