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Gene Expression Data
Assay Details
Assay
Reference: J:330830 Echevarria-Andino ML, et al., CDON contributes to Hedgehog-dependent patterning and growth of the developing limb. Dev Biol. 2022 Oct 17;493:1-11
Assay type: RNA in situ
MGI Accession ID: MGI:7411232
Gene symbol: Gli1
Gene name: GLI-Kruppel family member GLI1
Probe: Gli1 probe57
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 5A Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen 5A': embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 5A' Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen 5B: embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 5B Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen 5B': embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 5B' Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen 5C: embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 5C Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen 5C': embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1+ (more )
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 5C' Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen 5D: embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 5D Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen 5D': embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 5D' Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 5E Decreased expression in the most posterior portion.
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 5E' Decreased expression in the most posterior portion.
Specimen 5F: embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1tm2Fan, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 5F Severely decreased expression in the most posterior portion.
Specimen 5F': embryonic day 11.5; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1tm2Fan, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 5F' Severely decreased expression in the most posterior portion.
Specimen S3A: embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted S3A Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen S3A': embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS20: foot mesenchyme Present Regionally restricted S3A' Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen S3B: embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted S3B Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen S3B': embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: foot mesenchyme Present Regionally restricted S3B' Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen S3C: embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1+ (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted S3C Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen S3C': embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1+ (more )
Structure Level Pattern Image Note
TS20: foot mesenchyme Present Regionally restricted S3C' Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen S3D: embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted S3D Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Specimen S3D': embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: foot mesenchyme Present Regionally restricted S3D' Expressed in the posterior two-thirds of the limb bud mesenchyme, similar as in the wild-type.
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted S3E Decreased expression in the most posterior portion.
Specimen S3E': embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1tm2Fan (more )
Structure Level Pattern Image Note
TS20: foot mesenchyme Present Regionally restricted S3E' Decreased expression in the most posterior portion.
Specimen S3F: embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1tm2Fan, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted S3F Severely decreased expression in the most posterior portion.
Specimen S3F': embryonic day 12.0; Boctm2Rsk/Boctm2Rsk, Cdontm1c(EUCOMM)Hmgu/Cdontm1c(EUCOMM)Hmgu, Gas1tm2Fan/Gas1tm2Fan, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: foot mesenchyme Present Regionally restricted S3F' Severely decreased expression in the most posterior portion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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