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Gene Expression Data
Assay Details
Assay
Reference: J:129388 Aioub M, et al., Msx2 -/- transgenic mice develop compound amelogenesis imperfecta, dentinogenesis imperfecta and periodental osteopetrosis. Bone. 2007 Nov;41(5):851-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7410809
Gene symbol: Msx2
Gene name: msh homeobox 2
Reporter: lacZ
Direct Detection
Results
Specimen 5B: embryonic day 14.5; Msx2tm1Bero/Msx2tm1Bero (more )
Structure Level Pattern Image Note
TS22: limb Present 5B
TS22: mandible Present 5B
TS22: maxilla Present 5B
Specimen 5D: postnatal week 2; Msx2tm1Bero/Msx2tm1Bero (more )
Structure Level Pattern Image Note
TS28: molar root Strong 5E , 5D
TS28: periodontal ligament Strong 5E , 5D
TS28: mandible alveolar process Present Regionally restricted 5E , 5D Expression is higher in alveolar bone surrounding the erupting crown and in apical root elongation sites.
Specimen 5F: postnatal week 2; Msx2tm1Bero/Msx2tm1Bero (more )
Structure Cell Type Level Pattern Image Note
TS28: molar root osteoclast Present 5F Expression is in in root-forming cells, some periodontal cells and polynuclear osteoclasts that are in contact with bone.
TS28: periodontal ligament Present 5F
TS28: mandible alveolar process Present Regionally restricted 5F Expression is higher in alveolar bone surrounding the erupting crown and in apical root elongation sites.
Specimen 5G: postnatal week 2; Msx2tm1Bero/Msx2tm1Bero (more )
Structure Cell Type Level Pattern Image Note
TS28: molar crown osteoclast Present Regionally restricted 5G Expression is in polynuclear osteoclasts that are in contact with bone and facing the growing tooth.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory