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Gene Expression Data
Assay Details
Assay
Reference: J:36479 Jaskoll T, et al., Developmental expression and CORT-regulation of TGF-beta and EGF receptor mRNA during mouse palatal morphogenesis: correlation between CORT-induced cleft palate and TGF-beta 2 mRNA expression. Teratology. 1996 Jul;54(1):34-44
Assay type: Northern blot
MGI Accession ID: MGI:7398524
Gene symbol: Tgfb2
Gene name: transforming growth factor, beta 2
Probe: Tgfb2 probe12
Probe preparation: labelled with P32 DNA
Visualized with: Autoradiography
Results Image: 1_TGF-beta2
 Sample Information Bands Other Sample Information
Lane AgeStructure 6.1 kb 4.4 kb 3.7 kb Amount Genetic BackgroundMutant Allele(s)Sex
E13 -CORT E13.5 (a) TS21: palatal shelf Present Present Present 20 µg; total RNA B10.A/SgSn Not Specified
E13 +CORT Treated sample: no data stored
E14 -CORT E14.5 (a) TS22: palatal shelf Weak (b) Weak (b) Weak (b) 20 µg; total RNA B10.A/SgSn Not Specified
E14 +CORT Treated sample: no data stored
E15 -CORT E15.5 (a) TS23: palatal shelf Weak (c) Weak (c) Weak (c) 20 µg; total RNA B10.A/SgSn Not Specified
E15 +CORT Treated sample: no data stored
Notes:
(a) Age normalized so that noon of plug day = E0.5.
(b) Expression significanttly decreased (9%) from E13 to E14.
(c) Further drop in expression from E14 to E15; overall 20% decrease in expression from E13 to E15.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory