Ret RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:186470 Lopes C, et al., Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15
Assay type:	RNA in situ
MGI Accession ID:	MGI:7388623
Gene symbol:	Ret
Gene name:	ret proto-oncogene

Probe:	Ret probe23
Probe preparation:	Antisense RNA

Results

3A Control ©

Specimen 3A Control: postnatal day 30; Tlx3^tm2.1Qima/? (more

)
Note: Littermate control; genotype either fl/fl or fl/+. Double labeled: green - Ret; red - IB4.

Structure	Cell Type	Level	Pattern	Image	Note
TS28: lumbar dorsal root ganglion	neuron	Strong	Regionally restricted	3A Control	High level expression in 69% of IBF-positive neurons.

Specimen 3A Tlx3F/F;Nav1.8Cre/+: postnatal day 30; Tlx3^tm2.1Qima/Tlx3^tm2.1Qima, Tg(Scn10a-cre)1Rkun/0 (more

)
Note: Conditional mutant. Double labeled: green - Ret; red - IB4.

Structure	Cell Type	Level	Pattern	Image	Note
TS28: lumbar dorsal root ganglion	neuron	Weak	Regionally restricted	3A Tlx3F/F;Nav1.8Cre/+	Expression reduced in IBF4-positive neurons, but not fully lost. Expression in 18% of IBF-positive neurons.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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