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Gene Expression Data
Assay Details
Assay
Reference: J:217173 Lockhart MM, et al., Alk3 mediated Bmp signaling controls the contribution of epicardially derived cells to the tissues of the atrioventricular junction. Dev Biol. 2014 Dec 1;396(1):8-18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7388192
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67 (TEC-3; M7249)
Detection system: Secondary antibody
Results
Specimen not shown control: embryonic day 13.0; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant. Data was not shown and summarized in Fig. 5J and 5K.
Structure Level Pattern Image Note
TS21: atrioventricular sulcus Present
TS21: visceral pericardium Present
Specimen not shown cKO: embryonic day 13.0; Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant. Data was not shown and summarized in Fig. 5J and 5K.
Structure Level Pattern Image Note
TS21: atrioventricular sulcus Present Although there was a significant reduction in the total number of epicardially-derived cells, the percentage of proliferating cells was unchanged compared with the control.
TS21: visceral pericardium Present Similar as in the control.
Specimen not shown control: postnatal newborn; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: mitral valve Present Data was not shown and summarized in Table 2.
TS27: aortic valve Present
Specimen not shown cKO: postnatal newborn; Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: mitral valve Present Similar as in the control in the overall percentage of proliferating cells. Data was not shown and summarized in Table 2.
TS27: aortic valve Present Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory