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Gene Expression Data
Assay Details
Assay
Reference: J:327814 Suzuki D, et al., Dynamic Changes of Gene Expression in Mouse Mural Trophectoderm Regulated by Cdx2 During Implantation. Front Cell Dev Biol. 2022;10:945241
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378761
Gene symbol: Cdx2
Gene name: caudal type homeobox 2
Antibody: anti-Cdx2 (CDX2-88)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2D E3.5: embryonic day 3.5 (more )
Note: Double labeled: green - Cdx2; magenta - Eomes (assay MGI:7378762).
Structure Level Pattern Image Note
TS4: mural trophectoderm Present 2D Cdx2 E3.5 , 2D Merge E3.5
TS4: polar trophectoderm Present 2D Cdx2 E3.5 , 2D Merge E3.5

Specimen 2D E4.0: embryonic day 4.0 (more )
Note: Double labeled: green - Cdx2; magenta - Eomes (assay MGI:7378762).
Structure Level Pattern Image Note
TS5: polar trophectoderm Present 2D Cdx2 E4.0 , 2D Merge E4.0
TS5: mural trophectoderm Present 2D Merge E4.0 , 2D Cdx2 E4.0 Decreased expression compared with E3.5.

Specimen 2D E4.5: embryonic day 4.5 (more )
Note: Double labeled: green - Cdx2; magenta - Eomes (assay MGI:7378762).
Structure Level Pattern Image Note
TS6: polar trophectoderm Present 2D Cdx2 E4.5 , 2D Merge E4.5
TS6: mural trophectoderm Ambiguous 2D Cdx2 E4.5 , 2D Merge E4.5 Expression was completely repressed.

Specimen S1A blastocyst: embryonic day 3.5 (more )
Note: Double labeled: green - Cdx2; magenta - Sox2 (assay MGI:7378763).
Structure Level Pattern Image Note
TS4: mural trophectoderm Present S1A left
TS4: polar trophectoderm Present S1A left
TS4: inner cell mass Absent S1A left

Specimen S1A pTE + ICM: embryonic day 3.5 (more )
Note: Double labeled: green - Cdx2; magenta - Sox2 (assay MGI:7378763).
Structure Level Pattern Image Note
TS4: polar trophectoderm Present S1A middle
TS4: inner cell mass Absent S1A middle

Specimen S1A mTE: embryonic day 3.5 (more )
Note: Double labeled: green - Cdx2; magenta - Sox2 (assay MGI:7378763).
Structure Level Pattern Image Note
TS4: mural trophectoderm Present S1A right


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory