Gene Expression Data
Assay Details
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Assay
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Reference:
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J:137010
Petrou P, et al., Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome. J Biol Chem. 2005 Mar 18;280(11):10350-6
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7377701
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Gene symbol:
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Nkx2-1
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Gene name:
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NK2 homeobox 1
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Antibody:
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anti-TTF-1
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
4A:
embryonic day 16.5
(more  )
Specimen
4A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: lung epithelium |
Present |
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4A
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Expression is in the nuclei of all peripheral respiratory epithelial cells.
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Specimen
4B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * NMRI
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Mutant Allele(s):
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Fras1tm1Chpk/Fras1tm1Chpk
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: lung epithelium |
Present |
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4B
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Expression in this mutant is the same as in wild-type.
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Specimen
4C:
embryonic day 18.5
(more )
Specimen
4C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * NMRI
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Mutant Allele(s):
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Fras1tm1Chpk/Fras1tm1Chpk
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: alveolus epithelium |
type I pneumocyte |
Absent |
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4D
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Expression in this mutant is the same as in wild-type.
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Analysis Tools