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Gene Expression Data
Assay Details
Assay
Reference: J:137010 Petrou P, et al., Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome. J Biol Chem. 2005 Mar 18;280(11):10350-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7377694
Gene symbol: Fras1
Gene name: Fraser extracellular matrix complex subunit 1
Antibody: anti-Fras1
Detection system: Secondary antibody
Results
Specimen 1B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: visceral pleura Present Regionally restricted 1B Expression is underlying the mesothelial layer of the visceral pleura.
TS19: lung epithelium Present Regionally restricted 1B Expression is underlying the mesothelial layer of the airway epithelia.
Specimen 1C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: visceral pleura Present Regionally restricted 1C Expression is underlying the mesothelial layer of the visceral pleura.
TS24: lung epithelium Present Regionally restricted 1C Expression is underlying the mesothelial layer of the airway epithelia.
Specimen 1D: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: visceral pleura Present 1D
TS28: lung alveolus Absent 1D
Specimen 4G: embryonic day 18.5 (more )
Note: Double labeled: red - Fras1; green - Pecam1 (assay MGI:7377703).
Structure Level Pattern Image Note
TS26: alveolus epithelium Present 4G Expression is at the interface between endothelial and respiratory epithelial cells.
TS26: capillary endothelium Present 4G Expression is at the interface between endothelial and respiratory epithelial cells.
Specimen not shown: postnatal month 1 (more )
Structure Level Pattern Image Note
TS28: lung Absent Expression is absent in the lungs of mice older than 1 month.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory