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Gene Expression Data
Assay Details
Assay
Reference: J:329314 Wang Y, et al., Notch1 down-regulation in lineage-restricted niches is involved in the development of mouse eccrine sweat glands. J Mol Histol. 2022 Oct;53(5):857-867
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7346143
Gene symbol: Notch1
Gene name: notch 1
Antibody: anti-Notch1 (D1E11) (3608)
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 3a1,a2: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: foot Strong Widespread 3a1 , 3a2 Highly and widely expressed in skin basal layers, dermis and blood vessels.
Specimen 3b1,b2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: foot dermis Weak Regionally restricted 3b2 , 3b1 Expression significantly decreased all over dermis, especially in basal layers.
TS25: integumental system gland Trace Regionally restricted 3b2 , 3b1 Expressing cells almost disappeared in sweat gland buds.
Specimen 3c1,c2: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: plantar pad Weak Regionally restricted 3c1 , 3c2
TS27: sweat gland Trace 3c2 , 3c1 Expressing cells almost disappeared in newly-formed glandular structures.
Specimen 3d1,d2: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: plantar pad Weak Regionally restricted 3d2 , 3d1 Overall distribution of expression continuously decreased at P5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory