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Gene Expression Data
Assay Details
Assay
Reference: J:310743 Lin S, et al., Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) Specifically Interacts with Phospholipid Transfer Protein StarD10 to Facilitate Surfactant Phospholipid Trafficking in Alveolar Type II Cells. J Biol Chem. 2015 Jul 24;290(30):18559-74
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7345871
Gene symbol: Lpcat1
Gene name: lysophosphatidylcholine acyltransferase 1
Antibody: Anti-Lpcat1 (16112-1-AP)
Assay notes: This is an assay using the Duolink in situ proximity ligation assay (PLA) system (Olink Biosciences). PLA signal was only detected when both anti-Lpcat1 and anti-Stard10 antibodies were present.
Results
Specimen 3A wild type: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung Present 3A Wild type Merged , 3A Wild type PLA signal Proximity ligation signal was detected when both anti-Lpcat1 and and-StarD10 antibodies were present, as in the wild type.
Specimen 3A Lpcata1-/-: postnatal adult; Lpcat1tm1Tksh/Lpcat1tm1Tksh (more )
Structure Level Pattern Image Note
TS28: lung Weak 3A Lpcat1-/- Merged , 3A Lpcat1-/- PLA signal Proximity ligation signal was 7-fold lower in the mutant compared with wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory