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Gene Expression Data
Assay Details
Assay
Reference: J:226322 Roux M, et al., Hoxb1 regulates proliferation and differentiation of second heart field progenitors in pharyngeal mesoderm and genetically interacts with Hoxa1 during cardiac outflow tract development. Dev Biol. 2015 Oct 15;406(2):247-58
Assay type: RNA in situ
MGI Accession ID: MGI:7345658
Gene symbol: Myl2
Gene name: myosin, light polypeptide 2, regulatory, cardiac, slow
Probe: Mlc2v probe11
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present 1G
TS17: outflow tract Present Regionally restricted 1G Only expressed in the proximal region.
Specimen 1H: embryonic day 10.5; Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present 1H
TS17: outflow tract Present 1H Abnormally expressed in the distal region. The length was significantly reduced (see Fig 1K).
Specimen 1I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present 1I
TS17: outflow tract Present Regionally restricted 1I Only expressed in the proximal region.
Specimen 1J: embryonic day 10.5; Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present 1J
TS17: outflow tract Present 1J Abnormally expressed in the distal region. The length was significantly reduced (see Fig 1K).
Specimen 5A: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1+, Hoxb1tm5Mrc/Hoxb1+ (more )
Structure Level Pattern Image Note
TS15: outflow tract Present 5A
TS15: primitive ventricle Present 5A
Specimen 5B: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc, Hoxb1tm5Mrc/Hoxb1+ (more )
Structure Level Pattern Image Note
TS15: outflow tract Present 5B
TS15: primitive ventricle Present 5B
Specimen 5C: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1+, Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS15: outflow tract Present 5C
TS15: primitive ventricle Present 5C
Specimen 5D: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc, Hoxb1tm5Mrc/Hoxb1tm5Mrc (more )
Structure Level Pattern Image Note
TS15: outflow tract Present 5D
TS15: primitive ventricle Present 5D
Specimen S6A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: outflow tract Present S6A
TS15: primitive ventricle Present S6A
Specimen S6B: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Structure Level Pattern Image Note
TS15: outflow tract Present S6B Normal heart morphology as in the wild-type.
TS15: primitive ventricle Present S6B Normal heart morphology as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory