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Gene Expression Data
Assay Details
Assay
Reference: J:182446 Kon N, et al., Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice. J Biol Chem. 2012 Feb 10;287(7):5102-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7343906
Gene symbol: Huwe1
Gene name: HECT, UBA and WWE domain containing 1
Results
Specimen 2G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: embryo Present 2G

Specimen 3Ai: postnatal month 1; Huwe1tm1Wgu/Y (more )
Structure Cell Type Level Pattern Image Note
TS28: islets of Langerhans type B pancreatic cell Present 3Ai Expressed in nucleus and cytoplasm in some of the beta-cells.
TS28: islets of Langerhans pancreatic A cell Present 3Ai
TS28: pancreatic acinus pancreatic acinar cell Present 3Ai

Specimen 3Aiv: postnatal month 1; Huwe1tm1Wgu/Y, Tg(Ins2-cre)23Herr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: islets of Langerhans type B pancreatic cell Absent 3Aiv
TS28: islets of Langerhans pancreatic A cell Present 3Aiv Similar as in the control.
TS28: pancreatic acinus pancreatic acinar cell Present 3Aiv Similar as in the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory