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Gene Expression Data
Assay Details
Assay
Reference: J:242917 Meng Y, et al., Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos. Dev Dyn. 2017 Jul;246(7):517-530
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7343570
Gene symbol: Pten
Gene name: phosphatase and tensin homolog
Results
Specimen 2A WT E5.5: embryonic day 5.5 (more )
Note: The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: embryo Present 2A E5.5 WT
Specimen 2A WT E6.5: embryonic day 6.5 (more )
Note: The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: embryo Present 2A E6.5 WT
Specimen 2A - E5.5: embryonic day 5.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS8: embryo Absent 2A E5.5 -
Specimen 2A - E6.5: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: embryo Absent 2A E6.5 -
Specimen 2B WT: embryonic day 7.5 (more )
Note: The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS11: embryo Present 2B WT Pten
Specimen 2B -: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo Absent 2B - Pten Mutant embryos lacked an epiblast layer and exhibited abnormal cavitation.
Specimen 2C #1: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo Absent 2C #1 Pten Mutant embryos lacked an epiblast layer and exhibited abnormal cavitation.
Specimen 2C #2: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo Absent 2C #2 Pten Mutant embryos lacked an epiblast layer and exhibited abnormal cavitation.
Specimen 2C #3: embryonic day 7.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo Absent 2C #3 Pten Mutant embryos lacked an epiblast layer and exhibited abnormal cavitation.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory