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Gene Expression Data
Assay Details
Assay
Reference: J:242917 Meng Y, et al., Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos. Dev Dyn. 2017 Jul;246(7):517-530
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7343555
Gene symbol: Dab2
Gene name: disabled 2, mitogen-responsive phosphoprotein
Antibody: anti-Dab2
Detection system: Alexa Fluor
Assay notes: The authors did not specify which antibody was used, a rabbit antibody may have been used instead MGI:7341828.
Results
Specimen 1A WT: embryonic day 5.5 (more )
Note: Double labeled: green - Dab2; red - Pten (assay MGI:7343549). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: primitive endoderm Present 1A WT Merge , 1A WT Dab2
Specimen 1A Pten (-): embryonic day 5.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: green - Dab2; red - Pten (assay MGI:7343549).
Structure Level Pattern Image Note
TS8: primitive endoderm Present 1A - Dab2 , 1A - Merge Expression in this mutant is the same as in wild-type.
Specimen 1B #1 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #1 WT Dab2 , 1B #1 WT Merge
Specimen 1B #2 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #2 WT Dab2 , 1B #2 WT Merge
Specimen 1B #3 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #3 WT Dab2 , 1B #3 WT Merge
Specimen 1B #4 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #4 WT Merge , 1B #4 WT Dab2
Specimen 1B #5 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #5 WT Merge , 1B #5 WT Dab2
Specimen 1B #1 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #1 - Dab2 , 1B #1 - Merge
Specimen 1B #2 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #2 - Merge , 1B #2 - Dab2
Specimen 1B #3 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #3 - Dab2 , 1B #3 - Merge
Specimen 1B #4 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #4 - Dab2 , 1B #4 - Merge
Specimen 1B #5 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #5 - Merge , 1B #5 - Dab2
Specimen 3A Long.: embryonic day 5.5 (more )
Note: Double labeled: green - Dab2; red - Pten (assay MGI:7343549). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: primitive endoderm Present 3A Long. sec. Dab2 bottom , 3A Long. sec. Dab2 top , 3A Long. sec. Merge bottom , 3A Long. sec. Merge top
Specimen 3A Cross: embryonic day 5.5 (more )
Note: Double labeled: green - Dab2; red - Pten (assay MGI:7343549). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: primitive endoderm Present 3A Cross sec. Dab2 top , 3A Cross sec. Merge bottom , 3A Cross sec. Dab2 bottom , 3A Cross sec. Merge top
Specimen 4B WT: embryonic day 6.5 (more )
Note: Double labeled: green - Dab2; red - Prkcz (assay MGI:7343564). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 4B WT Merge , 4B WT Dab2
Specimen 4B -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: green - Dab2; red - Prkcz (assay MGI:7343564).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 4B - Dab2 , 4B - Merge
Specimen 4C WT: embryonic day 6.5 (more )
Note: Double labeled with Actin (red). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 4C WT Dab2 , 4C WT Merge
Specimen 4C -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled with Actin (red).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 4C - Merge , 4C - Dab2
Specimen 8E WT: embryonic day 5.5 (more )
Note: Double labeled: red - Dab2; green - Casp3 (assay MGI:7343569). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: primitive endoderm Present 8E WT
Specimen 8E -: embryonic day 5.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Casp3 (assay MGI:7343569)
Structure Level Pattern Image Note
TS8: primitive endoderm Present 8E -
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03/25/2025
MGI 6.24 		The Jackson Laboratory