About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:242917 Meng Y, et al., Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos. Dev Dyn. 2017 Jul;246(7):517-530
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7343555
Gene symbol: Dab2
Gene name: disabled 2, mitogen-responsive phosphoprotein
Antibody: anti-Dab2
Detection system: Alexa Fluor
Assay notes: The authors did not specify which antibody was used, a rabbit antibody may have been used instead MGI:7341828.
Results
Specimen 1A WT: embryonic day 5.5 (more )
Note: Double labeled: green - Dab2; red - Pten (assay MGI:7343549). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: primitive endoderm Present 1A WT Merge , 1A WT Dab2
Specimen 1A Pten (-): embryonic day 5.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: green - Dab2; red - Pten (assay MGI:7343549).
Structure Level Pattern Image Note
TS8: primitive endoderm Present 1A - Dab2 , 1A - Merge Expression in this mutant is the same as in wild-type.
Specimen 1B #1 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #1 WT Dab2 , 1B #1 WT Merge
Specimen 1B #2 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #2 WT Dab2 , 1B #2 WT Merge
Specimen 1B #3 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #3 WT Dab2 , 1B #3 WT Merge
Specimen 1B #4 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #4 WT Merge , 1B #4 WT Dab2
Specimen 1B #5 WT: embryonic day 6.5 (more )
Note: Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #5 WT Merge , 1B #5 WT Dab2
Specimen 1B #1 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #1 - Dab2 , 1B #1 - Merge
Specimen 1B #2 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #2 - Merge , 1B #2 - Dab2
Specimen 1B #3 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #3 - Dab2 , 1B #3 - Merge
Specimen 1B #4 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #4 - Dab2 , 1B #4 - Merge
Specimen 1B #5 -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Cdh1 (assay MGI:7343558).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 1B #5 - Merge , 1B #5 - Dab2
Specimen 3A Long.: embryonic day 5.5 (more )
Note: Double labeled: green - Dab2; red - Pten (assay MGI:7343549). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: primitive endoderm Present 3A Long. sec. Dab2 bottom , 3A Long. sec. Dab2 top , 3A Long. sec. Merge bottom , 3A Long. sec. Merge top
Specimen 3A Cross: embryonic day 5.5 (more )
Note: Double labeled: green - Dab2; red - Pten (assay MGI:7343549). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: primitive endoderm Present 3A Cross sec. Dab2 top , 3A Cross sec. Merge bottom , 3A Cross sec. Dab2 bottom , 3A Cross sec. Merge top
Specimen 4B WT: embryonic day 6.5 (more )
Note: Double labeled: green - Dab2; red - Prkcz (assay MGI:7343564). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 4B WT Merge , 4B WT Dab2
Specimen 4B -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: green - Dab2; red - Prkcz (assay MGI:7343564).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 4B - Dab2 , 4B - Merge
Specimen 4C WT: embryonic day 6.5 (more )
Note: Double labeled with Actin (red). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS9: primitive endoderm Present 4C WT Dab2 , 4C WT Merge
Specimen 4C -: embryonic day 6.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled with Actin (red).
Structure Level Pattern Image Note
TS9: primitive endoderm Present 4C - Merge , 4C - Dab2
Specimen 8E WT: embryonic day 5.5 (more )
Note: Double labeled: red - Dab2; green - Casp3 (assay MGI:7343569). The genetic background of this specimen was either wild-type or heterozygous.
Structure Level Pattern Image Note
TS8: primitive endoderm Present 8E WT
Specimen 8E -: embryonic day 5.5; Edil3Tg(Sox2-cre)1Amc/Edil3+, Ptentm1.1Hwu/Ptentm1.1Hwu (more )
Note: Conditional mutant. Double labeled: red - Dab2; green - Casp3 (assay MGI:7343569)
Structure Level Pattern Image Note
TS8: primitive endoderm Present 8E -
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory