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Gene Expression Data
Assay Details
Assay
Reference: J:327413 Gillnas S, et al., Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRalpha signalling in cerebellar development. Biol Open. 2022 Aug 15;11(8):bio059431
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7341420
Gene symbol: Calb1
Gene name: calbindin 1
Antibody: anti-Calbindin-D-28K (KD-25) (C2724)
Detection system: Secondary antibody
Results
Specimen 3A: postnatal day 0; Pdgfctm1Nagy/Pdgfc+, Pdgfratm11(EGFP)Sor/Pdgfra+ (more )
Note: Double labeled: red - Calb1; green - Pdgfra (assay MGI:7341419).
Structure Cell Type Level Pattern Image Note
TS27: cerebellum Purkinje cell Present 3A Purkinje cells evenly distributed at P0.
Specimen 3B: postnatal day 2; Pdgfctm1Nagy/Pdgfc+, Pdgfratm11(EGFP)Sor/Pdgfra+ (more )
Structure Cell Type Level Pattern Image Note
TS27: cerebellum Purkinje cell Present 3B
Specimen 3C: postnatal day 15; Pdgfctm1Nagy/Pdgfc+, Pdgfratm11(EGFP)Sor/Pdgfra+ (more )
Note: Double labeled: red - Calb1; green - Pdgfra (assay MGI:7341419).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present Regionally restricted 3C Purkinje cells in single layer at P15.
Specimen 3D: postnatal day 0; Pdgfctm1Nagy/Pdgfctm1Nagy, Pdgfratm11(EGFP)Sor/Pdgfra+ (more )
Note: Double labeled: red - Calb1; green - Pdgfra (assay MGI:7341419).
Structure Cell Type Level Pattern Image Note
TS27: cerebellum Purkinje cell Present Non-Uniform 3D Purkinje cells unevenly distributed with partly ectopic expression.
Specimen 3E: postnatal day 2; Pdgfctm1Nagy/Pdgfctm1Nagy, Pdgfratm11(EGFP)Sor/Pdgfra+ (more )
Structure Cell Type Level Pattern Image Note
TS27: cerebellum Purkinje cell Present Non-Uniform 3E Purkinje cells unevenly distributed with partly ectopic expression.
Specimen 3F: postnatal day 15; Pdgfctm1Nagy/Pdgfctm1Nagy, Pdgfratm11(EGFP)Sor/Pdgfra+ (more )
Note: Double labeled: red - Calb1; green - Pdgfra (assay MGI:7341419).
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell Present Clusters 3F Ectopic clusters of Purkinje cells in some areas.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory