Col2a1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:306318 Ono K, et al., Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2. Commun Biol. 2021 Mar 11;4(1):326
Assay type:	RNA in situ
MGI Accession ID:	MGI:7339222
Gene symbol:	Col2a1
Gene name:	collagen, type II, alpha 1

Probe:	Col2a1 cDNA21
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

4k WT Col2a1 ©

Specimen 4k WT: embryonic day 13.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS21: limb cartilage condensation	chondrocyte	Present		4k WT Col2a1

Specimen 4k -/-: embryonic day 13.5; Dmrt2^tm1Rjo/Dmrt2^tm1Rjo (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS21: limb cartilage condensation	chondrocyte	Present		4k -/- Col2a1	Similar as in the wild-type.

5a Col2a1 WT ©

Specimen 5a WT: embryonic day 14.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS22: tibia cartilage condensation	growth plate cartilage chondrocyte	Present		5a Col2a1 WT

Specimen 5a -/-: embryonic day 14.5; Dmrt2^tm1Rjo/Dmrt2^tm1Rjo (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS22: tibia cartilage condensation	growth plate cartilage chondrocyte	Present		5a Col2a1 Dmrt2-/-

5b Col2a1 WT ©

Specimen 5b WT: embryonic day 15.0 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS23: epiphyseal plate	growth plate cartilage chondrocyte	Present		5b Col2a1 WT

Specimen 5b -/-: embryonic day 15.0; Dmrt2^tm1Rjo/Dmrt2^tm1Rjo (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS23: epiphyseal plate	growth plate cartilage chondrocyte	Present		5b Col2a1 Dmrt2-/-	Similar as in the wild-type.

S6a WT ©

Specimen S6a WT: postnatal newborn (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: rib cartilage	chondrocyte	Present		S6a WT

S6a Dmrt2-/- ©

Specimen S6a -/-: postnatal newborn; Dmrt2^tm1Rjo/Dmrt2^tm1Rjo (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: rib cartilage	chondrocyte	Present		S6a Dmrt2-/-	Truncation, fusion, and bifurcation were seen.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24