About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:205338 Kuss P, et al., Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A. Dev Biol. 2014 Jan 1;385(1):83-93
Assay type: RNA in situ
MGI Accession ID: MGI:7336219
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: Ihh probe33
Probe preparation: Antisense RNA
Results
Specimen S2 E12.5 WT: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: forelimb digit mesenchyme chondrocyte Present Regionally restricted S2_wt-1 Expressed in metacarpals.
Specimen S2 E12.5 Spdh: embryonic day 12.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS20: forelimb digit mesenchyme Absent S2_spdh-1
Specimen S2 E13.5 WT: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: metacarpus pre-cartilage condensation chondrocyte Present Regionally restricted S2_wt-2 Expressed in the center of the anlage (prehypertrophic chondrocytes).
Specimen S2 E13.5 Spdh: embryonic day 13.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Cell Type Level Pattern Image Note
TS21: metacarpus pre-cartilage condensation chondrocyte Weak Regionally restricted S2_spdh-2 Expression was faint and reminiscent of the wild-type pattern at E12.5 indicating a delay in differentiation.
Specimen S2 E14.5 WT: embryonic day 14.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Cell Type Level Pattern Image Note
TS22: metacarpus cartilage condensation chondrocyte Present Regionally restricted S2_wt-4 Expressed in the center of the anlage (prehypertrophic chondrocytes).
Specimen S2 E14.5 Spdh: embryonic day 14.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Cell Type Level Pattern Image Note
TS22: metacarpus cartilage condensation chondrocyte Present S2_spdh-4 Expressed at a weaker level than in wild-type and with an apparent lack of central restriction.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory