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Gene Expression Data
Assay Details
Assay
Reference: J:276894 Dora E, et al., Loss of Pax6 Causes Regional Changes in Dll1 Expression in Developing Cerebral Cortex. Front Cell Neurosci. 2019;13:78
Assay type: RNA in situ
MGI Accession ID: MGI:7335046
Gene symbol: Dll1
Gene name: delta like canonical Notch ligand 1
Probe: Dll1 probe32
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Fluorescence
Assay notes: Authors state that non-homozygous littermates were used as controls.
Results
Specimen 6A: embryonic day 12.5; Pax6Sey/Pax6+ (more )
Note: The genetic background of the specimen was either wildtype or heterozygous. Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS20: telencephalon Present 6A Expression largely restricted to ventricular zone. No evidence of co-expression with Tbr2 at E12.5.
Specimen 6B: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS20: telencephalon Weak 6B Number of expressing cells greatly reduced compared to controls. No evidence fo co-expression with Tbr2.
Specimen 6C: embryonic day 12.5; Pax6Sey/Pax6+ (more )
Note: The genetic background of the specimen was either wildtype or heterozygous. Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 6C Expression largely restricted to ventricular zone. No evidence of co-expression with Tbr2 at E12.5.
Specimen 6D: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS20: telencephalon Weak 6D Number of expressing cells greatly reduced compared to controls. No evidence fo co-expression with Tbr2.
Specimen 6E: embryonic day 14.5; Pax6Sey/Pax6+ (more )
Note: The genetic background of the specimen was either wildtype or heterozygous. Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS22: telencephalon Present Regionally restricted 6E Expression largely confined to ventricular zone. No co-localization with Tbr2 expression.
TS22: hippocampus Present 6E Strong co-localization with Tbr2 expression in developing hippocampus.
Specimen 6F: embryonic day 14.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS22: telencephalon Weak 6F Many fewer expressing cells than in controls.
Specimen 6G: embryonic day 14.5; Pax6Sey/Pax6+ (more )
Note: The genetic background of the specimen was either wildtype or heterozygous. Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 6G Expression largely confined to ventricular zone. No co-localization with Tbr2 expression.
Specimen 6H: embryonic day 14.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Weak 6H Many fewer expressing cells than in controls.
Specimen 6I: embryonic day 14.5; Pax6Sey/Pax6+ (more )
Note: The genetic background of the specimen was either wildtype or heterozygous. Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 6I Expression largely confined to ventricular zone. No co-localization with Tbr2 expression.
Specimen 6J: embryonic day 14.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Weak 6J Many fewer expressing cells than in controls.
Specimen 6K: embryonic day 14.5; Pax6Sey/Pax6+ (more )
Note: The genetic background of the specimen was either wildtype or heterozygous. Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 6K Expression largely confined to ventricular zone. No co-localization with Tbr2 expression.
Specimen 6L: embryonic day 14.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: magenta - Dll1; green - Tbr2 (Eomes assay MGI:7335049).
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Weak 6L Many fewer expressing cells than in controls.
Specimen 7A: embryonic day 12.5; Pax6Sey/Pax6+ (more )
Note: The genetic background of the specimen was either wildtype or heterozygous. Double labeled: magenta - Dll1; green - Neurog2 (assay MGI:7335047).
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 7A Widely expression throughout progenitor zone. Many cells co-expressing Neurog2.
Specimen 7B: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: magenta - Dll1; green - Neurog2 (assay MGI:7335047).
Structure Level Pattern Image Note
TS20: cerebral cortex Weak Regionally restricted 7B Number of expressing cells greatly reduced compared to controls. Few cells co-expressing Neurog2.
Specimen 7C: embryonic day 12.5; Pax6Sey/Pax6+ (more )
Note: The genetic background of the specimen was either wildtype or heterozygous. Double labeled: magenta - Dll1; green - Neurog2 (assay MGI:7335047).
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 7C Widely expression throughout progenitor zone. Many cells co-expressing Neurog2.
Specimen 7D: embryonic day 12.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: magenta - Dll1; green - Neurog2 (assay MGI:7335047).
Structure Level Pattern Image Note
TS20: cerebral cortex Weak Regionally restricted 7D Number of expressing cells greatly reduced compared to controls. Few cells co-expressing Neurog2.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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