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Gene Expression Data
Assay Details
Assay
Reference: J:307271 Airik M, et al., Loss of Anks6 leads to YAP deficiency and liver abnormalities. Hum Mol Genet. 2020 Nov 4;29(18):3064-3080
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7333220
Gene symbol: Spp1
Gene name: secreted phosphoprotein 1
Antibody: anti-osteopontin (AF808)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5H: embryonic day 18.5 (more )
Note: Double labeled: red - OPN (Spp1); green - pan-cytokeratin.
Structure Level Pattern Image Note
TS26: intrahepatic bile duct epithelium Present Regionally restricted 5H Apical expression in biliary epithelial cells with normal apical polarization.
Specimen 5I: embryonic day 18.5; Anks6tm1d(KOMP)Wtsi/Anks6tm1d(KOMP)Wtsi (more )
Note: Double labeled: red - OPN (Spp1); green - pan-cytokeratin.
Structure Level Pattern Image Note
TS26: intrahepatic bile duct epithelium Present Regionally restricted 5I Expression on portal side, but missing from parenchymal side of bile ducts.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory