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Gene Expression Data
Assay Details
Assay
Reference: J:145763 Kawakami Y, et al., Impaired neurogenesis in embryonic spinal cord of Phgdh knockout mice, a serine deficiency disorder model. Neurosci Res. 2009 Mar;63(3):184-93
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7332838
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tubulin beta 3 (clone TUJ1, MMS-435P/801202)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4E: embryonic day 13.5 (more )
Note: Double labeled: green - Tubb3; red - Slc1a3 (assay MGI:7332839).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord neuron Present 4E , 4G
Specimen 4F: embryonic day 13.5; Phgdhtm1.1Shfu/Phgdhtm1.1Shfu (more )
Note: Double labeled: green - Tubb3; red - Slc1a3 (assay MGI:7332839).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord neuron Present 4H , 4F In this mutant the area of positive staining was reduced in the dorsal spinal cord and positive neurons had degenerated neurites.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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