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Gene Expression Data
Assay Details
Assay
Reference: J:173795 Hilliard S, et al., Tight regulation of p53 activity by Mdm2 is required for ureteric bud growth and branching. Dev Biol. 2011 May 15;353(2):354-66
Assay type: RNA in situ
MGI Accession ID: MGI:7330277
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Probe: Lhx1 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 11E: embryonic day 12.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep (more )
Structure Level Pattern Image Note
TS20: nephric duct Present 11E Wolffian duct.
TS20: renal vesicle Present 11E

Specimen 11F: embryonic day 12.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Hoxb7-cre)5526Cmb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: nephric duct Present 11F Wolffian duct. Reduced expression.
TS20: renal vesicle Present 11F Reduced expression in a lesser extent.

Specimen 12E: embryonic day 13.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep (more )
Structure Level Pattern Image Note
TS21: nephric duct Present 12E Wolffian duct.
TS21: renal vesicle Present 12E

Specimen 12F: embryonic day 13.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Hoxb7-cre)5526Cmb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: nephric duct Present 12F Wolffian duct. Reduced expression.
TS21: renal vesicle Present 12F Expressed in fewer nephrons and at lower levels compared with the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory