Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:173795 Hilliard S, et al., Tight regulation of p53 activity by Mdm2 is required for ureteric bud growth and branching. Dev Biol. 2011 May 15;353(2):354-66
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7330271
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved Caspase-3 (Asp175) (#9661)
Detection system:	Secondary antibody coupled to Alexa Fluor 555

Results

7A ©

7C ©

7F ©

7G ©

7J ©

Specimen 7A/C/F/G/J: embryonic day 14.5; Mdm2^tm1.2Mep/Mdm2^tm1.2Mep (more

)
Note: Double labeled: red - Casp3; green - cytokeratin.

Structure	Level	Pattern	Image	Note
TS22: ureter	Ambiguous	Single cells	7A , 7C , 7J , 7F , 7G

7B ©

7K ©

7N ©

7O ©

7R ©

Specimen 7B/K/N/O/R: embryonic day 14.5; Mdm2^tm1.2Mep/Mdm2^tm1.2Mep, Tg(Hoxb7-cre)5526Cmb/0 (more

)
Note: Conditional mutant. Double labeled: red - Casp3; green - cytokeratin.

Structure	Level	Pattern	Image	Note
TS22: ureter	Present		7B , 7R , 7N , 7K , 7O	Marked apoptosis, largely restricted to the apical borders.

7S ©

Specimen 7S: embryonic day 14.5; Mdm2^tm1.2Mep/Mdm2^tm1.2Mep (more

)
Note: Double labeled: red - Casp3; green - cytokeratin.

Structure	Level	Pattern	Image	Note
TS22: ureter	Ambiguous		7S

7T ©

Specimen 7T: embryonic day 14.5; Mdm2^tm1.2Mep/Mdm2^tm1.2Mep, Tg(Hoxb7-cre)5526Cmb/0 (more

)
Note: Conditional mutant. Double labeled: red - Casp3; green - cytokeratin.

Structure	Level	Pattern	Image	Note
TS22: ureter	Present		7T	Marked apoptosis, largely restricted to the apical borders.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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