About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:173286 Long JE, et al., Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
Assay type: RNA in situ
MGI Accession ID: MGI:7316423
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 probe35
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1YY: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 1YY
TS23: medial ganglionic eminence Weak 1YY

Specimen 1YY': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 1YY'
TS23: medial ganglionic eminence Present 1YY'

Specimen 1ZZ: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1ZZ

Specimen 1ZZ': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1ZZ' Expression is reduced in this mutant compared to controls.

Specimen S3O: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S3O
TS23: medial ganglionic eminence Present S3O

Specimen S3O': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S3O' Expression is decreased in this mutant compared to controls.
TS23: medial ganglionic eminence Present S3O' Expression is decreased in this mutant compared to controls.

Specimen S3O'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S3O''
TS23: medial ganglionic eminence Present S3O''

Specimen 3SP: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S3P

Specimen 3SP': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S3P' Expression is decreased in this mutant compared to controls.

Specimen 3SP'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S3P'' Expression is decreased in this mutant compared to controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory