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Gene Expression Data
Assay Details
Assay
Reference: J:173286 Long JE, et al., Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
Assay type: RNA in situ
MGI Accession ID: MGI:7316413
Gene symbol: Lhx6
Gene name: LIM homeobox protein 6
Probe: Lhx6 probe12
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1CC: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: globus pallidus Present 1CC
TS23: medial ganglionic eminence Present Regionally restricted 1CC Expression is in progenitor cells.
Specimen 1CC': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present 1CC' Expression is reduced in this mutant compared to controls.
TS23: globus pallidus Present Regionally restricted 1CC' In this mutant the globus pallidus is smaller with a reduced number of expressing neurons.
Specimen 1DD: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1DD
Specimen 1DD': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1DD' Expression is in ectopia that form in this mutant in a caudal position within the caudal ganglionic eminence.
Specimen S2E: embryonic day 15.5 (more )
Note: The genetic background of the control specimen was either wild type or heterozygous.
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S2E
Specimen S2E': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present S2E' Expression is in ectopia that form in this mutant in a caudal position within the caudal ganglionic eminence.
Specimen Table 1: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ganglionic eminence Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory