Gnaq Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:74178 Schuller U, et al., Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex. Histochem Cell Biol. 2001 Aug;116(2):149-59
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7314905
Gene symbol:	Gnaq
Gene name:	guanine nucleotide binding protein, alpha q polypeptide

Antibody:	anti-Gnaq (sc-393)
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

Specimen 2J: postnatal day 8 (more

)

Structure	Cell Type	Level	Image	Note
TS28: cerebellum Purkinje cell layer	Purkinje cell	Present	2J	Expression is moderate in the soma and dendrites.
TS28: cerebellum external granule cell layer		Weak	2J	There is a discrepancy between Table 3 and the figure legend. The table states expression is absent whereas Figure 2J states expression is weak at any developmental stages.
TS28: cerebellum internal granule cell layer		Weak	2J	There is a discrepancy between Table 3 and the figure legend. The table states expression is absent whereas Figure 2J states expression is weak at any developmental stages.

Specimen 2K: postnatal adult (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Purkinje cell	Strong		2K	Expression is moderate in the soma and dendrites.
TS28: cerebellum white matter		Present	Single cells	2K
TS28: cerebellum internal granule cell layer		Weak		2K
TS28: cerebellum molecular layer		Weak		2K

Specimen Table 3 P3: postnatal day 3 (more

)

Structure	Cell Type	Level	Note
TS27: cerebellum Purkinje cell layer	Purkinje cell	Moderate	Expression is moderate in the soma and absent in dendrites.
TS27: cerebellum external granule cell layer		Absent
TS27: cerebellum internal granule cell layer		Absent

Specimen Table 3 P5: postnatal day 5 (more

)

Structure	Cell Type	Level	Note
TS28: cerebellum Purkinje cell layer	Purkinje cell	Moderate	Expression is moderate in the soma and absent in dendrites.
TS28: cerebellum external granule cell layer		Absent
TS28: cerebellum internal granule cell layer		Absent

Specimen Table 3 P8: postnatal day 8 (more

)

Structure	Cell Type	Level	Note
TS28: cerebellum Purkinje cell layer	Purkinje cell	Moderate	Expression is moderate in the soma and dendrites.
TS28: cerebellum external granule cell layer		Absent	There is a discrepancy between Table 3 and the figure legend. The table states expression is absent whereas Figure 2J states expression is weak at any developmental stages.
TS28: cerebellum internal granule cell layer		Absent	There is a discrepancy between Table 3 and the figure legend. The table states expression is absent whereas Figure 2J states expression is weak at any developmental stages.

Specimen Table 3 P15: postnatal day 15 (more

)

Structure	Cell Type	Level	Note
TS28: cerebellum Purkinje cell layer	Purkinje cell	Moderate	Expression is moderate in the soma and weak in dendrites.
TS28: cerebellum molecular layer		Weak
TS28: cerebellum internal granule cell layer		Absent

Specimen Table 3 Adult: postnatal adult (more

)

Structure	Cell Type	Level	Note
TS28: cerebellum Purkinje cell layer	Purkinje cell	Moderate	Expression is moderate in the soma and absent in dendrites.
TS28: cerebellum internal granule cell layer		Moderate
TS28: cerebellum molecular layer		Weak

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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