Gene Expression Data
Assay Details
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Assay
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Reference:
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J:325429
Zhou HM, et al., Pax3 Hypomorphs Reveal Hidden Pax7 Functional Genetic Compensation in Utero. J Dev Biol. 2022 May 17;10(2)
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7287558
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Gene symbol:
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Pax7
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Gene name:
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paired box 7
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Antibody:
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anti-Pax7
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
3A:
(close  )
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Genetic Background:
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involves: 129X1/SvJ * C3H * C57BL/6
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Mutant Allele(s):
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Pax3tm1Sjc/Pax3tm1.2Sjc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: neural tube |
Strong |
Regionally restricted |
3A
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Expression is upregulated and dorsally expanded into the most dorsal region of the neural tube compared to wildtype littermate.
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| TS17: migrating neural crest |
Present |
Regionally restricted |
3A
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Ectopic expression in migrating neural crest cells adjacent to dorsal neural tube.
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Specimen
3B:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C3H * C57BL/6
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Mutant Allele(s):
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Pax3tm1Sjc/Pax3tm1.2Sjc
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: somite |
Strong |
Regionally restricted |
3B
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Expression upregulated and dorsally expanded in somites compared to wild type.
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Specimen
3C:
embryonic day 10.5
(more  )
Specimen
3C:
(close )
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Genetic Background:
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involves: 129X1/SvJ
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: neural tube |
Present |
Regionally restricted |
3C
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No expression in most dorsal region of neural tube.
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| TS17: migrating neural crest |
Absent |
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3C
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No expression in migrating neural crest cells adjacent to neural tube.
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Specimen
3D:
embryonic day 10.5
(more )
Specimen
3D:
(close )
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Genetic Background:
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involves: 129X1/SvJ
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Analysis Tools
