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Gene Expression Data
Assay Details
Assay
Reference: J:171508 Ikegami D, et al., Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
Assay type: RNA in situ
MGI Accession ID: MGI:7286336
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: Ihh probe30
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1D Sox9flox/+: embryonic day 14.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present 1D Ihh Sox9flox/+
Specimen 1D 11Enh-Cre; Sox9flox/flox: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)1Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Weak Regionally restricted 1D Ihh 11Enh-Cre; Sox9flox/flox Ihh expression was almost completely lost.
Specimen 3B Sox9flox/+: embryonic day 13.5; Sox9tm2Crm/Sox9+ (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present Regionally restricted 3B Ihh Sox9flox/+ Expression was detected in two domains.
Specimen 3B 11Prom-Cre; Sox9flox/flox: embryonic day 13.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present Regionally restricted 3B Ihh 11Prom-Cre; Sox9flox/flox The distance between the two Ihh expression domains was increased in the conditional mutant.
Specimen S2C Sox9flox/wt: embryonic day 15.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Level Pattern Image Note
TS23: humerus Present S2C Ihh Sox9flox/+
Specimen S2C 11Enh-Cre; Sox9flox/flox: embryonic day 15.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)1Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Level Pattern Image Note
TS23: humerus Absent S2C Ihh 11Enh-Cre;Sox9flox/flox
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory