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Gene Expression Data
Assay Details
Assay
Reference: J:168841 Lopes Floro K, et al., Loss of Cited2 causes congenital heart disease by perturbing left-right patterning of the body axis. Hum Mol Genet. 2011 Mar 15;20(6):1097-110
Assay type: RNA in situ
MGI Accession ID: MGI:7286311
Gene symbol: Dand5
Gene name: DAN domain family member 5, BMP antagonist
Probe: Dante probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S2A: embryonic day 7.5; Cited2tm1Jpmb/Cited2+ (more )
Note: early head fold stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS11: embryo Present S2A
Specimen S2B: embryonic day 7.5; Cited2tm1Jpmb/Cited2+ (more )
Note: late head fold stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS11: embryo Present S2B
Specimen S2C: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 1 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present S2C
Specimen S2D: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 1.5 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present S2D
Specimen S2E: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 2 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present S2E
Specimen S2F: embryonic day 7.5; Cited2tm1Jpmb/Cited2+ (more )
Note: early head fold stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS11: node Present S2F
Specimen S2G: embryonic day 7.5; Cited2tm1Jpmb/Cited2+ (more )
Note: late head fold stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS11: node Present S2G
Specimen S2H: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 1 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present S2H
Specimen S2I: embryonic day 8.0 (more )
Note: 1.5 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present Regionally restricted S2I Authors report a shift from bilateral to right sided expression in wild type embryos.
Specimen S2J: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 2 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present S2J
Specimen S2K: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 3 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present S2K
Specimen S2L: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 4 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present S2L
Specimen S2M: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 4 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present S2M
Specimen S2N: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 5 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present S2N
Specimen S2O: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 6 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present S2O
Specimen S2P: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 3 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present S2P
Specimen S2Q: embryonic day 8.0 (more )
Note: 4 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present Regionally restricted S2Q Authors report a shift from bilateral to right sided expression in wild type embryos.
Specimen S2R: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 4 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present S2R
Specimen S2S: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 5 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present S2S
Specimen S2T: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 6 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present S2T
Specimen 2A: embryonic day 8.0 (more )
Note: 4 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 2A Authors report a shift from bilateral to right sided expression in wild type embryos.
Specimen 2B: embryonic day 8.0 (more )
Note: 4 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 2B Authors report a shift from bilateral to right sided expression in wild type embryos.
Specimen 2C: embryonic day 8.0; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 3 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 2C Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen 2D: embryonic day 8.0; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 3 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 2D Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen 2E: embryonic day 8.0; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 3 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 2E Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen 2F: embryonic day 8.0; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 3 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 2F Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen 2G: embryonic day 8.0; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 4 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 2G Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Specimen 2H: embryonic day 8.0; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 4 somite stage. Double labeled: blue - Dand5; blue - Uncx (assay MGI:7286314).
Structure Level Pattern Image Note
TS12: node Present Regionally restricted 2H Abnormal expression in a subset of Cited2 null embryos. Expression was either not detected or there was a left-sided bias.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory