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Gene Expression Data
Assay Details
Assay
Reference: J:311933 Kong JH, et al., Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength. Development. 2021 Oct 1;148(19):dev199867
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7279116
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-SOX2
Results
Specimen S6B SOX2 Control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present S6B SOX2 Control
Specimen S6B SOX2 Mosmo-/-: embryonic day 10.5; Mosmoem1Rroh/Mosmoem1Rroh (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present S6B SOX2 Mosmo-/- Authors report normal neural tube patterning
Specimen S6C SOX2 Control: embryonic day 10.5 (more )
Note: Triple labeled: blue - Sox2; green - Arl13b (assay MGI:7279115); red - Smo (assay MGI:7279114).
Structure Cell Type Level Pattern Image Note
TS17: future spinal cord neural progenitor cell Present S6C Control (merge left) Expression within spinal neural progenitors.
Specimen S6C SOX2 Mosmo-/-: embryonic day 10.5; Mosmoem1Rroh/Mosmoem1Rroh (more )
Note: Triple labeled: blue - Sox2; green - Arl13b (assay MGI:7279115); red - Smo (assay MGI:7279114).
Structure Cell Type Level Pattern Image Note
TS17: future spinal cord neural progenitor cell Present S6C Mosmo-/- (merge left) Expression within spinal neural progenitors.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory