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Gene Expression Data
Assay Details
Assay
Reference: J:82311 Yamamoto M, et al., Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate. Development. 2003 May;130(9):1795-804
Assay type: RNA in situ
MGI Accession ID: MGI:7266654
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2 probe34
Probe preparation: Antisense RNA
Results
Specimen 2H: embryonic day 8.2 (more )
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 2H There is asymmetric left-sided expression.
TS12: branchial arch Present 2H
Specimen 2I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present 2I There is asymmetric left-sided expression.
TS15: branchial arch Present 2I
Specimen 2J: embryonic day 8.2; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 2J Asymmetric left-sided expression was absent in two-thirds (29/43) of the mutant embryos.
TS12: branchial arch Present 2J In this mutant the bilateral expression in the branchial arch was the same as in wild-type.
Specimen 2K: embryonic day 9.5; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: embryo Present Regionally restricted 2K Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: branchial arch Present 2K In this mutant the bilateral expression in the branchial arch was the same as in wild-type.
Specimen 2L: embryonic day 8.2; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Weak Regionally restricted 2L There is a reduced level of left-sided expression in the lateral plate mesoderm.
TS12: branchial arch Present 2L In this mutant the bilateral expression in the branchial arch was the same as in wild-type.
Specimen 2M: embryonic day 9.5; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: embryo Present Regionally restricted 2M Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: branchial arch Present 2M In this mutant the bilateral expression in the branchial arch was the same as in wild-type.
Specimen 2N: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: common atrial chamber Present Regionally restricted 2N There is asymmetric left-sided expression.
TS15: common cardinal vein Present Regionally restricted 2N There is asymmetric left-sided expression.
TS15: gut Present Regionally restricted 2N There is asymmetric left-sided expression.
TS15: lung Present Regionally restricted 2N There is asymmetric left-sided expression.
TS15: mesenchyme derived from lateral plate Present Regionally restricted 2N There is asymmetric left-sided expression.
TS15: sinus venosus Present Regionally restricted 2N There is asymmetric left-sided expression.
TS15: vitelline vein Present Regionally restricted 2N There is asymmetric left-sided expression.
Specimen 2O: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: common atrial chamber Present Regionally restricted 2O There is asymmetric left-sided expression.
TS15: common cardinal vein Present Regionally restricted 2O There is asymmetric left-sided expression.
TS15: gut Present Regionally restricted 2O There is asymmetric left-sided expression.
TS15: lung Present Regionally restricted 2O There is asymmetric left-sided expression.
TS15: mesenchyme derived from lateral plate Present Regionally restricted 2O There is asymmetric left-sided expression.
TS15: sinus venosus Present Regionally restricted 2O There is asymmetric left-sided expression.
TS15: vitelline vein Present Regionally restricted 2O There is asymmetric left-sided expression.
Specimen 2P: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: common atrial chamber Present Regionally restricted 2P There is asymmetric left-sided expression.
TS15: common cardinal vein Present Regionally restricted 2P There is asymmetric left-sided expression.
TS15: gut Present Regionally restricted 2P There is asymmetric left-sided expression.
TS15: lung Present Regionally restricted 2P There is asymmetric left-sided expression.
TS15: mesenchyme derived from lateral plate Present Regionally restricted 2P There is asymmetric left-sided expression.
TS15: sinus venosus Present Regionally restricted 2P There is asymmetric left-sided expression.
TS15: vitelline vein Present Regionally restricted 2P There is asymmetric left-sided expression.
Specimen 2Q: embryonic day 9.5; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: embryo Present Regionally restricted 2Q Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
Specimen 2R: embryonic day 9.5; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: embryo Present Regionally restricted 2R Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
Specimen 2S: embryonic day 9.5; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: embryo Present Regionally restricted 2S Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
Specimen 2T: embryonic day 9.5; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: common atrial chamber Weak Regionally restricted 2T Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: common cardinal vein Weak Regionally restricted 2T Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: gut Weak Regionally restricted 2T Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: lung Weak Regionally restricted 2T Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: mesenchyme derived from lateral plate Weak Regionally restricted 2T Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: sinus venosus Weak Regionally restricted 2T Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: vitelline vein Weak Regionally restricted 2T Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
Specimen 2U: embryonic day 9.5; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: common atrial chamber Weak Regionally restricted 2U Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: common cardinal vein Weak Regionally restricted 2U Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: gut Weak Regionally restricted 2U Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: lung Weak Regionally restricted 2U Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: mesenchyme derived from lateral plate Weak Regionally restricted 2U Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: sinus venosus Weak Regionally restricted 2U Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: vitelline vein Weak Regionally restricted 2U Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
Specimen 2V: embryonic day 9.5; Foxh1tm1Hmd/Foxh1tm1.1Hmd, Tg(Leftb-cre)1Hmd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: common atrial chamber Weak Regionally restricted 2V Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: common cardinal vein Weak Regionally restricted 2V Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: gut Weak Regionally restricted 2V Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: lung Weak Regionally restricted 2V Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: mesenchyme derived from lateral plate Weak Regionally restricted 2V Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: sinus venosus Weak Regionally restricted 2V Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
TS15: vitelline vein Weak Regionally restricted 2V Asymmetric left-sided expression was absent in ~70% (18/26) of the mutant embryos.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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