Yap1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:308788 Cheong SS, et al., The Planar Polarity Component VANGL2 Is a Key Regulator of Mechanosignaling. Front Cell Dev Biol. 2020;8:577201
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7266323
Gene symbol:	Yap1
Gene name:	yes-associated protein 1

Antibody:	anti-YAP (D8H1X) XP#14074
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

6A WT ©

6B WT ©

Specimen 6A/B WT: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: bronchiole epithelium	Present		6A WT , 6B WT	Expressed in the nuclei.
TS26: lung mesenchyme	Present		6B WT , 6A WT	Expressed in the nuclei of a proportion of mesenchymal cells.

6A Lp/+ ©

6B Lp/+ ©

Specimen 6A/B Lp/+: embryonic day 18.5; Vangl2^Lp/Vangl2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS26: bronchiole epithelium	Present		6B Lp/+ , 6A Lp/+	Expressed in the nuclei. The percentage of positive cells was significantly decreased compared with wild-type control.
TS26: lung mesenchyme	Present		6B Lp/+ , 6A Lp/+	Expressed in the nuclei of a proportion of mesenchymal cells.

6A Lp/Lp ©

6B Lp/Lp ©

Specimen 6A/B Lp/Lp: embryonic day 18.5; Vangl2^Lp/Vangl2^Lp (more

)

Structure	Level	Pattern	Image	Note
TS26: bronchiole epithelium	Present		6A Lp/Lp , 6B Lp/Lp	Expressed in the nuclei. The percentage of positive cells was significantly decreased compared with wild-type control.
TS26: lung mesenchyme	Present		6B Lp/Lp , 6A Lp/Lp	Expressed in the nuclei of a proportion of mesenchymal cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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