Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:61488
Pennisi D, et al., Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice. Nat Genet. 2000 Apr;24(4):434-7
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:7266262
|
Gene symbol:
|
Sox18
|
Gene name:
|
SRY (sex determining region Y)-box 18
|
Probe:
|
Sox18 probe3
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
Visualized with:
|
Alkaline phosphatase
|
|
Results
|
Specimen
1a:
embryonic day 7.5
(more )
Specimen
1a:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 7.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
1b:
embryonic day 8.0
(more )
Specimen
1b:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 8.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
1c:
embryonic day 8.5
(more )
Specimen
1c:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
1d:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Flt1tm1Jrt/Flt1tm1Jrt
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: vascular system |
Present |
Regionally restricted |
1d
|
Expression in pattern reflecting disturbed blood vessel development
|
Specimen
1e:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Kdrtm1Jrt/Kdrtm1Jrt
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
1g:
embryonic day 9.5
(more )
Specimen
1g:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
1h:
embryonic day 11.0
(more )
Specimen
1h:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
1i:
embryonic day 12.5
(more )
Specimen
1i:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
1j:
embryonic day 8.0
(more )
Specimen
1j:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 8.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS12: yolk sac mesenchyme |
|
Present |
|
1j
|
|
TS12: vascular system |
gut endothelial cell |
Present |
Regionally restricted |
1j
|
Expression in endothelial cells around foregut.
|
TS12: cardiogenic plate |
endocardial cell |
Present |
Regionally restricted |
1j
|
Expression in presumptive endocardial cells of cardiogenic plate.
|
Specimen
1k:
embryonic day 9.5
(more )
Specimen
1k:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS15: dorsal aorta |
aortic endothelial cell |
Present |
Regionally restricted |
1k
|
Expression in presumptive endocardial cells of cardiogenic plate.
|
Specimen
1l:
embryonic day 9.5
(more )
Specimen
1l:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS15: intersomitic blood vessel |
blood vessel endothelial cell |
Present |
Regionally restricted |
1l
|
Expression in endothelial cells of intersomitic vessels.
|
TS15: yolk sac mesenchyme |
endothelial cell |
Present |
|
1l
|
Expression in endothelial cells of yolk sac mesoderm.
|
Specimen
1m:
embryonic day 9.5
(more )
Specimen
1m:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS15: intersomitic blood vessel |
blood vessel endothelial cell |
Present |
|
1m
|
Expression in endothelial cells of intersomitic vessel.
|
Specimen
2a:
embryonic day 14.0
(more )
Specimen
2a:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 14.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
not shown:
embryonic day 15.0
(more )
Specimen
not shown:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 15.0
|
Sex:
|
Not Specified
|
Type:
|
Not Specified
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: vibrissa follicle |
Present |
|
|
Expression in vibrissae follicle persisted until E15.0.
|
Specimen
2b:
embryonic day 14.0
(more )
Specimen
2b:
(close )
Genetic Background:
|
CD-1
|
Age:
|
embryonic day 14.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: vibrissa dermal component |
Present |
Regionally restricted |
2b
|
Expression in underlying mesenchyme adjacent to epithelial placode, persists in mesenchymal cells surrounding invaginating epithelium until dermal papillae stage.
|
|