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Gene Expression Data
Assay Details
Assay
Reference: J:190555 Yoon Y, et al., Conditional Aurora A deficiency differentially affects early mouse embryo patterning. Dev Biol. 2012 Nov 1;371(1):77-85
Assay type: RNA in situ
MGI Accession ID: MGI:7264811
Gene symbol: Hhex
Gene name: hematopoietically expressed homeobox
Probe: Hex cDNA
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Edil3Tg(Sox2-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 3A Control
TS9: primitive streak Present Regionally restricted 3A Control Expression at tip of primitive streak.
Specimen 3A Epi-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Edil3Tg(Sox2-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present Regionally restricted 3A Epi-KO Expression in anterior visceral endoderm prperly located on one side of epiblast, extending from tip of epiblast to junction with extraembryonic ectoderm.
TS9: embryo Present Regionally restricted 3A Epi-KO No expression on posterior side of embryo.
TS9: primitive streak Absent 3A Epi-KO
Specimen 6C Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 6C Control
Specimen 6C VE-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present Regionally restricted 6C VE-KO Expression at tip of embryo.
Specimen 6D Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 6D Control
Specimen 6D VE-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present Regionally restricted 6D VE-KO Expression shifted to one side of epiblast, failing to reach epiblast/extraembryonic ectoderm boundary.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory