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Gene Expression Data
Assay Details
Assay
Reference: J:190555 Yoon Y, et al., Conditional Aurora A deficiency differentially affects early mouse embryo patterning. Dev Biol. 2012 Nov 1;371(1):77-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7264809
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase-3 (Asp175) (5A1E; #9664)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 2D Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Edil3Tg(Sox2-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: conceptus Ambiguous 2D Control Author do not describe expression in control.
Specimen 2D Epi-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Edil3Tg(Sox2-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: proamniotic cavity Strong 2D Epi-KO Strong expression in proamniotic cavity, indicating presence of apoptotic cells.
Specimen 6B Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: conceptus Ambiguous 6B Control Author do not describe expression in control.
Specimen 6B VE-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: embryonic visceral endoderm Strong 6B VE-KO Extensive expression in visceral endoderm layer of embryo.
TS9: embryo Present Regionally restricted 6B VE-KO Expression mostly restricted to embryonic portion of egg cylinder.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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