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Gene Expression Data
Assay Details
Assay
Reference: J:278751 Hatakeyama J, et al., Hes1 and Hes5 regulate the development of the cranial and spinal nerve systems. Dev Neurosci. 2006;28(1-2):92-101
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7264782
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tuj1
Results
Specimen 6E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 6E Mesencephalic neurons were differentiated in the alar plate.

Specimen 6F: embryonic day 9.5; Hes1tm1Fgu/Hes1tm1Fgu, Hes5tm1Fgu/Hes5tm1Fgu (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 6F Mesencephalic neurons were differentiated in the alar plate, similar as in the wild-type.

Specimen 7D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 7D
TS17: future spinal cord Present 7D
TS17: spinal nerve Present 7D The ventral roots from the motor neurons and the dorsal roots from the dorsal root ganglion were formed.

Specimen 7E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 7E
TS17: future spinal cord Present 7E
TS17: spinal nerve Present 7E The ventral roots from the motor neurons and the dorsal roots from the dorsal root ganglion were formed.

Specimen 7I: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Fgu, Hes5tm1Fgu/Hes5tm1Fgu (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 7I
TS17: spinal nerve Present 7I Neurons of the dorsal root ganglion and spinal cord were intermingled.

Specimen 7I': embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Fgu, Hes5tm1Fgu/Hes5tm1Fgu (more )
Structure Level Pattern Image Note
TS17: spinal nerve Present 7I' Axonal projections from the motor neurons were poorly formed.

Specimen 7J: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Fgu, Hes5tm1Fgu/Hes5tm1Fgu (more )
Structure Level Pattern Image Note
TS17: spinal nerve Present 7J Neurons of the dorsal root ganglion and spinal cord were intermingled.
TS17: dorsal root ganglion Present 7J

Specimen 7K: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Fgu, Hes5tm1Fgu/Hes5tm1Fgu (more )
Structure Level Pattern Image Note
TS17: spinal nerve Present 7K Axonal projections from the motor neurons were poorly formed. Neurons of the dorsal root ganglion and spinal cord were intermingled.
TS17: dorsal root ganglion Present 7K


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory