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Gene Expression Data
Assay Details
Assay
Reference: J:221397 Vanyai HK, et al., Mesodermal expression of Moz is necessary for cardiac septum development. Dev Biol. 2015 Jul 1;403(1):22-9
Assay type: RNA in situ
MGI Accession ID: MGI:7264742
Gene symbol: Tbx5
Gene name: T-box 5
Probe: Tbx5 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4C: embryonic day 9.5; Mesp1tm2(cre)Ysa/Mesp1+ (more )
Structure Level Pattern Image Note
TS15: secondary heart field Present Regionally restricted 4C Expression in dorsal mesenchymal protrusion (DMP).
TS15: forelimb bud Present 4C
Specimen 4D: embryonic day 9.5; Kat6atm2.1Avo/Kat6atm2.1Avo, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: secondary heart field Weak Regionally restricted 4D Expression reduced in dorsal mesenchymal protrusion (DMP).
TS15: forelimb bud Present 4D Expression unaffected in forelimb bud.
Specimen 4G: embryonic day 10.5; Mesp1tm2(cre)Ysa/Mesp1+ (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present Regionally restricted 4G Expression in left ventricle.
TS17: forelimb bud Present 4G
Specimen 4H: embryonic day 10.5; Kat6atm2.1Avo/Kat6atm2.1Avo, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: primitive ventricle Weak Regionally restricted 4H Expression substantially decreased in left ventricle.
TS17: forelimb bud Present 4H Expression only moderately affected in forelimb.
Specimen 4G': embryonic day 10.5; Mesp1tm2(cre)Ysa/Mesp1+ (more )
Structure Level Pattern Image Note
TS17: heart atrium Present Regionally restricted 4G' Expression in right atrium.
TS17: secondary heart field Present 4G'
TS17: lung rudiment mesenchyme Present 4G' Expression in nascent pulmonary mesoderm.
Specimen 4H': embryonic day 10.5; Kat6atm2.1Avo/Kat6atm2.1Avo, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: heart atrium Weak Regionally restricted 4H' Expression decreased in right atrium.
TS17: secondary heart field Weak 4H' Expression decreased in second heart field.
TS17: lung rudiment mesenchyme Weak 4H' Expression decreased in nascent pulmonary mesoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory