Gene Expression Data
Assay Details
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Assay
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Reference:
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J:311536
Kim BJ, et al., RERE deficiency causes retinal and optic nerve atrophy through degeneration of retinal cells. Dev Dyn. 2021 Oct;250(10):1398-1409
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7262902
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Gene symbol:
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Pou4f2
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Gene name:
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POU domain, class 4, transcription factor 2
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Results
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Specimen
7A:
embryonic day 15.5
(more  )
Specimen
7A:
(close  )
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Genetic Background:
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involves: 129S6/SvEvTac * BTBR * C57BL/6
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS23: retina layer |
retinal ganglion cell |
Present |
Regionally restricted |
7A
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Specimen
7B:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * BTBR * C57BL/6
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Mutant Allele(s):
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Rereeyes3/Rereom
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS23: retina layer |
retinal ganglion cell |
Present |
Regionally restricted |
7B
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The distribution of retinal ganglion cells in the mutant was comparable with the wild type.
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Specimen
7C:
embryonic day 17.5
(more )
Specimen
7C:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * BTBR * C57BL/6
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS25: retina layer |
retinal ganglion cell |
Present |
Regionally restricted |
7C
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Expression was detected in retinal ganglion cells in the neuroblast layer and the ganglion cell layer.
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Specimen
7D:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * BTBR * C57BL/6
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Mutant Allele(s):
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Rereeyes3/Rereom
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS25: retina layer |
retinal ganglion cell |
Present |
Regionally restricted |
7D
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Expression was detected in retinal ganglion cells in the neuroblast layer and the ganglion cell layer. However, the density of retinal ganglion cells was significantly decreased in the mutant compared with wild type littermates.
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Specimen
7E:
postnatal day 7
(more )
Specimen
7E:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * BTBR * C57BL/6
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
7F:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac * BTBR * C57BL/6
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Mutant Allele(s):
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Rereeyes3/Rereom
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina ganglion cell layer |
retinal ganglion cell |
Present |
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7F
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The population of retinal ganglion cells of the mutant was less than that of wild type littermates.
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Analysis Tools