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Gene Expression Data
Assay Details
Assay
Reference: J:168038 Bimonte S, et al., Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91
Assay type: RNA in situ
MGI Accession ID: MGI:7258468
Gene symbol: Ptch1
Gene name: patched 1
Probe: Ptch1 probe29
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 7D: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: ulna columnar chondrocyte Present Regionally restricted 7D Expression in columnar and prehypertrophic chondrocytes.
TS24: ulna growth plate cartilage chondrocyte Present Regionally restricted 7D Expression in columnar and prehypertrophic chondrocytes.
TS24: perichondrium Present 7D
Specimen 7E: embryonic day 16.5; Ofd1tm2.1Bfra/Ofd1+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: ulna Weak 7E Expression dramatically reduced compared to wildtype.
TS24: perichondrium Weak 7E Expression in perichondrium. significantly reduced compared with wildtype.
Specimen 7F: embryonic day 16.5; Ofd1tm2.1Bfra/Y, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: ulna Trace 7F Expression dramatically reduced compared to wildtype.
TS24: perichondrium Trace 7F Expression barely detected in perichondrium of male mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory