Shh RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:110602 Lin L, et al., Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis. Dev Biol. 2006 Jul 15;295(2):756-63
Assay type:	RNA in situ
MGI Accession ID:	MGI:7258332
Gene symbol:	Shh
Gene name:	sonic hedgehog

Probe:	Shh probe209
Probe preparation:	RNA

Results

1A ©

Specimen 1A: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1A
TS13: notochord	Present		1A
TS13: foregut diverticulum endoderm	Present	Regionally restricted	1A	Expression in ventral pharyngeal/foregut endoderm.

1B ©

Specimen 1B: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1B
TS13: notochord	Present		1B
TS13: foregut diverticulum endoderm	Present	Regionally restricted	1B	Expression in ventral pharyngeal/foregut endoderm.

1C ©

Specimen 1C: embryonic day 8.5; Smo^tm1Amc/Smo^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1C
TS13: notochord	Present		1C
TS13: foregut diverticulum endoderm	Weak	Regionally restricted	1C	Expression selectively dowregulated in ventral pharyngeal/foregut endoderm relative to control littemates.

1D ©

Specimen 1D: embryonic day 8.5; Smo^tm1Amc/Smo^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1D
TS13: notochord	Present		1D
TS13: foregut diverticulum endoderm	Weak	Regionally restricted	1D	Expression selectively dowregulated in ventral pharyngeal/foregut endoderm relative to control littemates.

1E ©

Specimen 1E: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1E
TS13: notochord	Present		1E
TS13: foregut diverticulum endoderm	Present	Regionally restricted	1E	Expression in ventral pharyngeal/foregut endoderm.

1F ©

Specimen 1F: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1F
TS13: notochord	Present		1F
TS13: foregut diverticulum endoderm	Present	Regionally restricted	1F	Expression in ventral pharyngeal/foregut endoderm.

1G ©

Specimen 1G: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1G
TS13: notochord	Present		1G
TS13: foregut diverticulum endoderm	Present	Regionally restricted	1G	Expression in ventral pharyngeal/foregut endoderm.

1H ©

Specimen 1H: embryonic day 8.5; Smo^tm1Amc/Smo^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1H
TS13: notochord	Present		1H
TS13: foregut diverticulum endoderm	Weak	Regionally restricted	1H	Expression selectively dowregulated in ventral pharyngeal/foregut endoderm relative to control littemates.

1I ©

Specimen 1I: embryonic day 8.5; Smo^tm1Amc/Smo^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1I
TS13: notochord	Present		1I
TS13: foregut diverticulum endoderm	Weak	Regionally restricted	1I	Expression selectively dowregulated in ventral pharyngeal/foregut endoderm relative to control littemates.

1J ©

Specimen 1J: embryonic day 8.5; Smo^tm1Amc/Smo^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS13: neural tube floor plate	Present		1J
TS13: notochord	Present		1J
TS13: foregut diverticulum endoderm	Weak	Regionally restricted	1J	Expression selectively dowregulated in ventral pharyngeal/foregut endoderm relative to control littemates.

3G ©

Specimen 3G: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: branchial arch endoderm	Present		3G
TS15: foregut epithelium	Present		3G

3H ©

Specimen 3H: embryonic day 9.5; Smo^tm1Amc/Smo^tm2Amc, Isl1^tm1(cre)Sev/Isl1⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS15: branchial arch endoderm	Present		3H	Expression not affected compared with control littermates.
TS15: foregut epithelium	Present		3H	Expression not affected compared with control littermates.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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